Context and consequences of substance use, misuse, and dependence: a global imperative

Alexander Tsai of Partners.org and Harvard et al analysed the harms of opioid use and their determinants, as well as interventions, gaps in literature and the way forward – Substance use, misuse, and dependence harms extend far beyond their corrosive effects on health, safety and wellbeing to include healthcare expenditures, productivity losses, criminal justice involvement, social harm and more.