High-potency cannabis: psychiatry’s next challenge

When our parents were young, marijuana contained about 4% THC, its main psychoactive compound. Today you find products routinely approaching 20% THC. Concentrates and extracts up THC to 70%-95%. “We have not simply cultivated a plant; we have bioengineered it into something pharmacologically unrecognizable from its ancestors,” Garrett Rossi MD warned in Psychiatric Times.