Frequent cannabis use increases epileptic seizures

Frequent use of cannabis by people with hard-to-treat epilepsy was linked to greater illness severity and other health burdens, according to Washington University et al. Some patients with epilepsy use cannabis due to perceived benefits – but an analysis found that frequent users were admitted to a hospital epilepsy monitoring unit sooner after diagnosis than nonusers: 5 years vs 18 years.

Frequent users were also found to have a higher prevalence and frequency of focal to bilateral tonic–clonic seizures – associated with sudden, unexpected death. Among frequent cannabis users, over 90% had the condition compared to nonusers’ 57%. Moreover, researchers discovered that patients with frequent cannabis use had increased antiseizure medication requirements.

Patients who used cannabis frequently were found to have been “discharged on a greater number of antiseizure medications,” even though the number of medications were similar during admission, according to the study.

Dr. Aaron Struck, senior author of the study, said that the findings indicate that the issue of cannabis use should be raised directly with patients.